Propofol Induced Seizure like Phenomenon During Modified Electroconvulsive Therapy

Authors

  • Divya R Nair Assistant Professor,Department Of Psychiatry,Father Muller Medical College,Mangalore,Karnataka Author
    • Rajmohan Velayudhan Professor, Department of Psychiatry, KMCT Medical College, Kerala Author https://orcid.org/0000-0002-5468-2305
      • Raghuram Thazhe Mangool Emeritus Professor, Department Of Psychiatry,MES Medical College,Perinthalmanna,Kerala Author
        • Ajith Premnath Associate Professor,Department Of Psychiatry,MES Medical College,Perinthalmanna,Kerala Author

          DOI:

          https://doi.org/10.30834/KJP.37.2.2024.466

          Keywords:

          Propofol, Seizure, Seizure like phenomenon (SLP), Modified Elecroconvulsive Therapy (MECT)

          Abstract

          Background: Propofol is an intravenous anesthetic that is said to have anticonvulsant properties. This is a case report of the propofol-induced seizure-like phenomenon (SLP) during modified (MECT).

          Case Report: A 24-year-old female with severe depression without psychotic symptoms and borderline personality disorder underwent six sessions of MECT. During the earlier session of MECT using thiopentone as an anesthetic, a prolonged seizure occurred, indicating a low seizure threshold. Then, it was changed to propofol. When propofol was given as an induction agent, even before giving ECT, the patient developed seizure-like involuntary jerking movements.  EEG and MRI were done after the fourth session and were found normal.

          Discussion: This case report highlights that even though propofol has anticonvulsant activity, few cases of SLP during procedures have been reported. Propofol-induced SLP during MECT is the first of its kind.

           

           

          Conflict of Interest: Rajmohan Velayudhan: The article was submitted on 30 July 2024. On 12 August, the author became editor-in-chief of the Journal. Adhering to COPE Guidelines, the previous editor and section editor processed and decided on the article. The current editor-in-chief was not involved in any processing or decision-making phase.

          The other authors have no conflict of interest. 

          References

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          Published

          18-12-2024

          Issue

          Section

          Case Report

          How to Cite

          1.
          Propofol Induced Seizure like Phenomenon During Modified Electroconvulsive Therapy. Kerala Journal of Psychiatry [Internet]. 2024 Dec. 18 [cited 2026 Aug. 27];37(2):136-8. Available from: https://www.kjponline.com/index.php/kjp/article/view/466

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